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In addition to the conditions mentioned above, several risk factors increase the likelihood of B12 deficiency: Smoking Alcohol abuse Endocrine-related autoimmune disorders (such as diabetes or thyroid disorders) Gastrointestinal disorders like Crohns disease History of gastric bypass surgery or other stomach-altering surgeries Optimize Your Health
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A multidisciplinary panel of endocrinologists recently advised clinicians to extend the dose-escalation phase or pause dose increases if patients are experiencing GI adverse effects (source)
A study published in JAMA found that individuals using GLP-1 receptor agonists had a higher incidence of gallbladder-related problems compared to those on placebo
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