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Taken as a once-weekly injection Doses studied so far include: 1 mg, 4 mg, 8 mg, and up to 12 mg Gradual dose increases are used to help the body adjust and reduce side effects Because retatrutide is still in development, the exact dosing schedule could change before it becomes available, but the general approach is expected to feel similar to current GLP-1 medications
However, cysteine has been shown to accumulate in tissues of patients with glutathione synthetase deficiency at least in cultured fibroblasts [24]
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