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16 Transfer of these vesicles to previously untreated recipient tubular cells induces a canonical ferroptotic phenotype, including loss of GPX4, accumulation of lipid ROS, increased malondialdehyde levels, and progressive membrane damage

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Delayed gastric emptying, gastroparesis-like symptoms, intestinal obstruction, biliary disease, and pancreatic safety concerns were variably reported, with heterogeneous and sometimes conflicting evidence across studies

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