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Therefore, the notable efficacy of nAbs in established Ebola virus infection in monkeys and humans, even when symptoms are present, is perhaps a surprise, albeit an encouraging one for nAb therapies, given the severity and rapid spread of Ebola virus infection in vivo 157,158,159
The most common side effects are gastrointestinal: nausea (affecting ~25% of patients, usually mild and transient), diarrhea, constipation, and decreased appetite
Exenatide and lixisenatide are exendin based GLP-1 receptor agonists