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When released in response to dietary fat in the small intestine, CCK binds to CCK1 receptors on vagal afferent neurons, initiating a cascade that activates these neurons and transmits signals to the NTS in the brainstem
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Be sure to drink plenty of fluids, especially water, throughout the day
Conclusion From a weird gut hormone that lasted two minutes to blockbuster drugs changing how we treat diabetes, obesity, heart disease, and maybe more, the journey of GLP-1 agonists has been nothing short of remarkable
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