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Because it reduces appetite and makes you feel satisfied after meals, semaglutide can lead to significant weight loss when combined with a healthy diet and regular physical activity

Combining two individually beneficial interventions does not always produce additive or synergistic results

Less commonly associated side effects include hypoglycemia, acute pancreatitis, increased risk of gallbladder and biliary diseases, renal insufficiency or acute renal failure, retinopathy, and thrombocytopenia (low platelet count)