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Common adverse effects include nausea, vomiting, diarrhoea, and constipation, which are generally most pronounced during dose escalation

Dei Cas A, Spigoni V, Cito M, Aldigeri R, Ridolfi V, Marchesi E, Marina M, Derlindati E, Aloe R, Bonadonna RC, Zavaroni I

- Tirzepatide versus Semaglutide Once Weekly in a Type 2 Diabetes Study (SURPASS-2, NEJM 2021) Semaglutide Prescribing Information Reference (FDA, 2025) Tirzepatide Prescribing Information Reference (FDA, 2025) What Real Users Say When the Drug Choice Turns Into Daily Life The Comparison Starts With the Drug

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