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The enzyme dipeptidyl peptidase 4 (DPP-IV) cleaves it between the second and third residues which renders it inactive within several minutes, and explains why GLP-1 cannot be used as a drug itself
Low-Extraction Drugs (Low E): These drugs are not significantly metabolized on the first pass and therefore tend to have a high oral bioavailability (F is high)
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The role of lipids and membranes in the pathogenesis of Alzheimer's disease: a comprehensive view
