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Side effects and safety profile Across the combined Phase 3 Tesamorelin database of over 800 treated subjects, the most frequently reported adverse events were injection site reactions (erythema, pruritus, small local hematoma) at roughly 25 percent of subjects, arthralgia and myalgia at 10 to 15 percent, and peripheral edema at 6 to 8 percent

The inversion is what deserves attention: prediabetes is an explicit qualifier

1.91 pp CagriSema Semaglutide 1.5-1.8 pp Tirzepatide 2.0-2.4 pp Retatrutide 1.6-2.0 pp Parameter Notable differentiator Cagrilintide Amylin pathway

For someone on a GLP-1 medication, this leads to a cycle of feeling "waterlogged" yet remaining dehydrated at a cellular level