Patients with features such as rapid progression, significant asymmetry, predominant motor symptoms, severe autonomic dysfunction, or unexplained weight loss should receive expedited evaluation, as these may indicate alternative or additional diagnoses requiring different management approaches
Its core mechanisms are closely related to disorders of cellular energy metabolism, accumulation of oxidative stress, and reduced capacity for DNA damage repair
They observed mobilization of Pax7+ satellite cells, improved fibrillar regeneration, and a reduction in fibrosis
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