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This fold is characteristic of the N-terminal nucleophile (Ntn) hydrolase superfamily (Kim et al., 2000), glycosylasparaginase ( Molecular Mechanism of Autoprocessing Through several mutational and crystallography studies, it was demonstrated for the first time in EcGGT that the processing was an autocatalytic event rather than a, earlier hypothesized, protease-dependent occurrence (Kuno et al., 1984)

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Khansaheb M, Choi JY, Joo NS, Yang YM, Krouse M, Wine JJ