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17 While ERAD was previously thought to be associated with PQC, which safeguards protein maturation, recent studies have demonstrated that ERAD also regulates the abundance of folding-competent proteins as a means to fine-tune key physiological processes, suggesting that ERAD constitutively functions to ensure both protein fidelity and abundance
The metabolism of homocysteine involves three pivotal processes: S-adenosyl-l-methionine (SAM)-dependent transmethylation, folate-dependent or -independent remethylation cycles, and transsulfuration reactions
however, results across chronic inflammatory conditions are inconsistent
Our results indicated that NAC effectively promoted the differentiation of TSPCs and the repair of injured tendons in rats
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