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3.18], respectively, and 3.02 kg [ 3.82

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A physical barrier is provided by epithelial cells in the gut, which serves as the guts main line of defense, and in addition to fighting pathogens, it limits their direct contact with epithelium by working with immune cells and stromal cells ( However, symbiotic bacteria are not harmless and can induce severe inflammatory reactions such as colitis and septicemia if they enter the systemic immune system