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As proteostasis capacity becomes constrained, newly synthesized polypeptides requiring high chaperone support for proper folding may become increasingly vulnerable, rendering neuronal cells more susceptible to damage
Mutations in SOD1 are considered oxidative stress-inducing factors in ALS pathogenesis
TiO2-ZnPc nanoparticles functionalized with folic acid as a target photosensitizer for photodynamic therapy against glioblastoma cells
For example, ketamine is a non-competitive antagonist of the NMDA glutamate receptor, which has been shown to quickly reduce depressive symptoms, anxiety, and PTSD (5761)
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