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The effects of T-RDN on responses of increases in urine flow and sodium excretion to GLP-1 were not significantly different from those observed with A-RDN
A clinical review published in 2025 proposed that GLP-1 agonist modulation via increased serotonergic activity at the 5-HT2C receptor may result in diminished sexual desire
Therefore, it will be of interest to determine the effect of metabolic health on the effects of GLP-1R agonists in future work
If maximum average weight loss is the priority and injection is acceptable, Mounjaro may be the better fit
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