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Who Should Be Especially Careful People with diabetes, gastroparesis, pancreatitis history, or eating disorders should get personalized medical advice before major diet or medication changes
For example, ER stress can promote acinar cell apoptosis by activating the p53/AIFM2 axis and the PERKJNK pathway, 252,253,254,264 induce caspase-1-dependent pyroptosis via activation of the PERK pathway, 265 and trigger necroptosis in pancreatic acinar cells by enhancing CTSB maturation and activating the PKCJNKc-Jun cascade
Elife 8 , e45572 (2019)
I.BrandM
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