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In the future, longitudinal studies will be necessary to capture trajectories of changes over time in AC levels and depressive symptoms in order to properly disentangle trait vs state effects and provide empirical grounding for causal interpretation, triangulating evidence with experimental medicine approaches

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WEGOVY tablets are indicated in combination with a reduced calorie diet and increased physical activity: to reduce the risk of major adverse CV events (CV death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established CV disease and either obesity or overweight