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Cell migration: In vitro studies have observed TB-500 influencing the migration of keratinocytes, endothelial cells, and fibroblasts in wound models Integrin-linked kinase (ILK) activation: Preclinical data suggest Thymosin Beta-4 activates ILK, which may play a role in cell survival signaling in experimental cardiac models Angiogenic signaling: TB-500 has been observed to stimulate endothelial cell migration and tube formation in in vitro angiogenesis assays

[1] If the solution is drawn into a syringe for injection, it should be administered promptly for the same reason (avoid leaving the filled syringe exposed to light for long)

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Other metabolites with VIP score 1 were GSH (Fig