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Its gene-level effects are unparalleled in their breadth

Community estimates suggest that source quality explains approximately 80% of the variation in user outcomes

Guidelines from bodies such as the Endocrine Society and AACE (American Association of Clinical Endocrinology) recommend considering GLP-1 RAs (or other anti-obesity medications) in patients with BMI 30, or 27 with weight-related comorbidities, when lifestyle measures alone are insufficient

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