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Despite the enticing claims made in the advertising for energy drinks, says Kerner, research on the effectiveness and safety of most herbal supplements and other ingredients contained in them is very limited at this time. The Verdict

Off-label use of semaglutides continued to grow in 2022 for those with employer-sponsored insurance

Retatrutide does not yet have the same routine-care evidence base

Given the high frequency of musculoskeletal problems in individuals with clEDS (Supplementary Table 1), we propose that coordination of care and follow-up for patients with clEDS lie with (pediatric) rheumatology and if available with specialized EhlersDanlos services