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This differential processing of APP is determined by the cellular localization of each secretase, with -secretases predominantly expressed on the cell surface, whereas and -secretases mostly localize in the acidic environment of the endolysosome system (Zhang and Song, 2013)

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Safety What Researchers Should Watch For Its naturally present in human blood, so the toxicity profile starts in a pretty good place

LEfSe analysis provided a secondary measure to establish differences between treatment groups in addition to the one-way ANOVA/KruskalWallis tests performed on each genus/phylum