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Neuroscience (2017) 357:24154
Molecular mechanisms of biological aging in intervertebral discs
Your body has had more time to establish new metabolic set points and adapt to a lower weight
Both MT-2 and leptin are thought to cause an increase in TRH expression in the paraventricular nucleus of the hypothalamus, a region of the brain associated with satiety and food intake, but only MT-2 crosses into the central nervous system in concentrations high enough to have an effect on TRH expression
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