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Muskiet added that the true blood-pressure-lowering effect of GLP-1s may actually be underestimated in the review

Kanikowska A, Janisz S, Mankowska-Wierzbicka D, Gabryel M, Dobrowolska A, Eder P

These metabolic improvements extend beyond glycaemic control, with emerging evidence suggesting favourable effects on various cardiovascular risk factors, including blood pressure and lipid profiles

What happened: The 503B Bulks List proposal On April 30, 2026, the FDA announced it is proposing to exclude semaglutide, tirzepatide, and liraglutide from the 503B Bulk Drug Substances List

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