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Even mild endothelial dysfunction (e.g., due to oxidative stress or inflammation) impairs this regulatory axis, facilitating arterial stiffening and predisposing individuals to hypertension

Heterotopic transplantation of cryopreserved ovarian tissue in cancer patients: a case series

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1 Consequently, while multi-receptor agonists represent a promising future direction in obesity pharmacotherapy, their application in adolescents must be interpreted cautiously, with careful consideration of developmental safety, long-term outcomes, and ethical implications of extrapolating adult data to younger populations