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Coffee increases gastric acid secretion, stimulates intestinal motility, and has mild diuretic propertiesthough for habitual coffee drinkers, caffeinated beverages generally count towards daily fluid intake with minimal net dehydrating effect
The most common adverse effects include nausea (12-24%), diarrhea (12-17%), decreased appetite (10-14%), vomiting (6-12%), constipation (11-17%), dyspepsia, and abdominal pain
acetylation, methylation or glycosylation), transduce the information on the cell metabolic status, and modulate the activities of signaling proteins, enzymes, and transcriptional regulators 3
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