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& Swanstrom, R
MT-II is a cyclic heptapeptide broadly activating MC1R, MC3R, and MC4R , simultaneously producing melanogenesis alongside central pro-sexual, pro-erectile, and anorectic effects through hypothalamic MC3R/MC4R activation, Cyclisation of the -MSH pharmacophore core is the primary structural determinant of this receptor subtype selectivity shift
My doctor was surprised (in a good way)
AMS Edmonton, Alberta Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, OReilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, OConnell J, & OShea D (2011)
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