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10.1038/s41574-022-00783-3 31 HavranekB.LohR.TorreB.RedfieldR.Halegoua-DemarzioD
Seek medical advice if you experience: New or worsening vision problems Severe or progressive weakness Loss of coordination or balance Confusion or cognitive changes Seizures These symptoms could indicate underlying conditions requiring investigation
These concerns are increasingly common in patients who have lost weight rapidly, naturally or with GLP-1 medications
Its worth stating that most clinical trials, even the largest ones, deliver average effects of treatments, and very few trials can reliably estimate treatment-effect differences in subgroups, and even fewer can estimate individualized responses to treatments
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