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This Fos expression was reduced by ghrelin administration before 30 min (left NG 21.7% and right NG 20.4%) (Fig
It also uniquely slashed inflammation, as measured by high-sensitivity C-reactive protein, by about 43% compared to placebo Another study found that activating GLP-1 receptors in the brain dramatically lowered inflammation in mice, cutting the surge of TNF- and easing inflammation-related harm during sepsis
The breadth of these effects is the point: the receptor does not appear to act through a single disease-specific mechanism but through a general increase in neuronal resilience
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