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10.1016/j.ab.2017.07.009 Summary Keywords cytochrome P450, blood-brain barrier, epilepsy, drug interaction, apoptotic signaling, pharmacodynamics, SIRT3 Citation Ghosh C, Westcott R, Perucca E, Hossain M, Bingaman W and Najm I (2022) Cytochrome P450-mediated antiseizure medication interactions influence apoptosis, modulate the brain BAX/Bcl-X L ratio and aggravate mitochondrial stressors in human pharmacoresistant epilepsy
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Semaglutide is a relatively stable peptide, but aggressive agitation creates shearing forces that can degrade any protein-based molecule
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