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As we get older, our bodies produce less elastin, which is why skin can start to sag or take longer to snap back into place
However, some candidate mechanisms have been proposed, namely, the impairment of AKT translocation through the activation of atypical PKC, and the activation of PP2A [132,133]
Safety findings were based on analysis of serious AEs only and do not incorporate other AEs that may be meaningful to an elderly population, such as non-serious gastrointestinal AEs
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