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Senescent cell SASP (senescence-associated secretory phenotype) suppression is an emerging GHK-Cu research area: GHK-Cu reduces SA--galactosidase activity (senescence marker), p16/p21 expression, and SASP cytokine secretion (IL-6, IL-8, GDF15) in hydrogen peroxide-induced premature senescence models mechanistically through NF-B suppression and p53 pathway modulation
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Unlike many popular anti-aging treatments that work by removing or irritating the skins surface layers to trigger renewal, GHK-Cu takes a more cooperative approach
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