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2018, doi: 10.1007/s00296-018-4142-x Chourpiliadis, C., et al, "Use of Common Psychiatric Medications and Risk and Prognosis of Amyotrophic Lateral Sclerosis," JAMA Network Open, June 4, 2024, doi:10.1001/jamanetworkopen.2025.14437 Meron, M.K., et al, "GLP-1 receptor agonists and the risk of fragility fractures in older adults with type 2 diabetes," Journal of Clinical Endocrinology & Metabolism, Feb.10, 2026, doi: 10.1210/clinem/dgag056 Luo, Y., et al, "GLP-1 receptor agonists in eye disease: a comprehensive review of current research and future potential," BMC Ophthalmology, Jan
In these cases, the introduction of semaglutide might smooth out the diarrheal phases but could potentially lengthen the constipation phases
These include the severity of deficiency, patient age, and malabsorption issues