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Normal and cancerous tissues release extrachromosomal circular DNA (eccDNA) into the circulation

One of the most important risk factors for glaucoma is elevated intraocular pressure (IOP), which promotes mechanical stress in RGCs and the lamina cribrosa, blockading axonal transport and causing axonal degeneration 3,4

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In addition, while individuals with renal insufficiency are at higher risk of developing CAD compared to those with normal kidney function, that risk was not found to be greater with low rather than normal selenium concentrations in serum (98 g/L vs