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A 4% drop in absolute LBM accompanying a 12% drop in body weight gives roughly 20% of weight loss as 'lean tissue.' Batsis reports closer to 35% and as Langer makes clear later in this piece, the gap between those numbers is partly explained by what DXA actually counts as 'lean

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Photo by Innerbody Research In 2023, one published review counted more than 80 approved peptide drugs on the pharmaceutical market, and the number has almost certainly grown since then.1 Thats a lot to keep track of, and most people are aware of just a handful a few for weight loss, and maybe a couple that weightlifters use to improve their gains

How can we think that manipulating our GLP or GIP production in such drastic ways would not have a downstream impact somewhere else