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10.1016/j.ijbiomac.2022.01.070 179 ZuoS.WangG.HanQ.XiaoH.HO

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In The High Costs of Low-Grade Inflammation, Dantzer points out that during chronic inflammation, insulin resistance in the brain decreases glucose and protein metabolism in the astrocytes, forcing the neurons to rely more heavily on the less efficient process of lipid metabolism for energy