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It depends on the source
The most consistently documented side effect of excessive B12 is dermatological reactions, particularly acne-like eruptions and rosacea flare-ups
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A 2013 study assessed several studies examining the impact of B12 on longevity in patients with kidney disease, and all six studies yielded the same result: there were more surviving patients in the groups that did not supplement B12, and fewer in those who did supplement.[1] Whereas, in people with healthy kidneys, this trend is either not seen at all or found to be the opposite in research
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