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Margulies KB, Hernandez AF, Redfield MM et al (2016) Effects of liraglutide on clinical stability among patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial
Generally, GLP-1s are well tolerated and dont appear to cause severe adverse events in most people, particularly semaglutide
The results from the Boston collaborators raised questions about the physiological way that GLP-1 prompted the release of insulin, a phenomenon described as an 'insulinotropic effect' (Drucker, Philippe, Mojsov)
Indeed, one may consider the ability of insulin to control the hepatic GH sensitivity to be a normal physiological response to changes in nutrition
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