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Research use therefore focuses on mechanism, target validation, and combinatorial experiments (e.g., with dietary change or NAD precursors) [14,8,9]

doi: 10.1016/j.crohns.2012.07.010 238 RastegarpanahMMalekzadehRVahediHMohammadiMElahiEChaharmahaliMet al

Other ACTIVITY GOAL This article reviews the mechanisms by which NMDA receptor dysfunction might lead to the complex patterns of symptoms and neurocognitive deficits seen in schizophrenia and on methods by which glutamate-based theories can be used to develop new treatment methodologies