Busquets S, Serpe R, Toledo M, Betancourt A, Marmonti E, Orpi M, Pin F, Capdevila E, Madeddu C, Lopez-Soriano FJ, et al
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The guideline from the American Association of Clinical Endocrinology (AACE/ACE) recommends GLP-1 receptor agonists as preferred pharmacologic agents for obesity with metabolic comorbidities, with preference for agents showing the greatest efficacy and tolerability in the individual patient [14]
Unlike symptomatic treatments (gabapentinoids, duloxetine), ALC promotes actual nerve fiber regeneration and addresses underlying pathophysiology.[17][2] This disease-modifying potential makes it particularly valuable for early intervention