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**** Thyroid function disturbances **** Potential for kidney dysfunction , leading even to kidney failure Severe abdominal pain Incorrect technique of injection (especially by an untrained person) can result in sepsis, HIV, & other infections Conclusions There is no published data for either the safety or efficacy of glutathione injections for skin lightening.There is very little evidence that establishes either the safety or efficacy of glutathione injections for skin lightening

Here too there are several mechanisms in effect simultaneously: B12 is a strong antioxidant that has proven almost as potent as superoxide dismutase (oxidative stress) (68) B12 is a scavenger of nitrogen radicals and also controls their production (nitrosative stress) (69, 70) B12 plays a role in the creation of glutathione , a central antioxidant (71) Through all of these mechanisms, vitamin B12 plays an important regulating role in all inflammatory diseases and in this way, protects the health of the nerves

HRR HR deficiency is characteristic of many HGSOC cases (approximately 50%) and is considered a predictive biomarker of sensitivity to platinum agents and PARPis [42]