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A prospective randomized controlled trial has shown that pretreatment with CoQ10 can significantly increase the number of high-quality early embryos in young women who have a decreased ovarian reserve and a low prognosis (Xu et al., 2018)

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Human umbilical cord blood- derived culture mast cells pre-treated with luteolin at 100 mol/l inhibited the IgE-mediated release of VEGF in another study [168]