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Brown E, Heerspink HJL, Cuthbertson DJ, Wilding JPH

The study, which lasts 1.5 years, is split into two components, with participants either receiving trial drug or being assigned to a weight-loss diet in the first component, and all participants receiving the trial drug in the second component

01 Increases intracellular NAD+ approximately 02 Activates SIRT1 longevity pathway 03 Reduces adipocyte size by Anti-Aging & Longevity 5-Amino-1MQ is a small molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme upregulated in obesity and aging

13, 25 May 2022, www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.889923/full