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Tirzepatide and Liraglutide microdosing Similar to semaglutide microdosing, tirzepatide microdosing is an off-label practice of taking a weekly dose of tirzepatide (brand names Mounjaro or Zepbound) that is lower than the FDA-approved 2.5 mg starting dose to reduce common gastrointestinal side effects and potentially lower the cost by making the medication last longer
It also allows for incredible flexibility in dosing
A 2024 in vivo/in vitro study confirmed its potential to suppress skin inflammation and improve transepidermal water loss (TEWL) in atopic dermatitis models
In the following, we review the preclinical and clinical evidence of GIP receptor antagonism
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