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[5] [6] Similarly, individuals with pre-existing fatigue, anaemia, or other comorbidities may find that GLP-1 therapy temporarily exacerbates their symptoms

For most people it is mild to moderate and improves over the following weeks

448 Indeed, deletion of EAAT1 astrocytic glutamate transporter translates into OCD-like phenotype manifested by excessive self-grooming and repetitive tic-like head shake 449 arguably linked to hyperactive resting state activity and aberrant functional connectivity of the cortico-striatal-thalamic circuitry as revealed by diffusion functional magnetic resonance imaging

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