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10.1111/1541-4337.12539 6 Ben-MeirA.BursteinE.Borrego-AlvarezA.ChongJ.WongE.YavorskaT.et al (2015)

It's currently labeled as a category 2 substance, meaning that the FDA has identified an ingredient as having a possible safety risk and it cannot be used in compounded medications

10.1016/j.theriogenology.2020.10.015 15