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Barretts esophagus Symptoms The development of Barretts esophagus is most often attributed to long-standing GERD, which may include these signs and symptoms: Frequent heartburn and regurgitation of stomach contents Difficulty swallowing food Less commonly, chest pain Curiously, approximately half of the people diagnosed with Barretts esophagus report little if any symptoms of acid reflux

The intravenously administered macrocylic peptidomimetic molecule ulimorelin, enhanced gastric emptying, and was subsequently mainly studied in critical care patients, with lack of differentiation from metoclopramide (50, 51)

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