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Completely bald areas where follicles have died and scarred over won't respond

24(12):9837 Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E et al (2021) Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries

Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk

Future efforts must prioritize multi-center trials for safety/PK profiling, biodegradable polymers with tunable degradation, and multi-omics biomarkers for personalized therapy