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*Correspondence: Predrag Sikiric, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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While pain tolerance varies among individuals, clinical trials have not identified injection site pain as a significant reason for stopping treatment