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Understanding this cascade is what separates a substantiated research finding from a marketing claim it explains why certain effects appear early at the cellular level while others require weeks of sustained signaling to become measurable
Miller KJ, Bowsher RR, Celniker A et al (2001) Workshop on bioanalytical methods validation for macromolecules: summary report
214 STAT3 also sequesters FOXO transcription factors in the cytoplasm, preventing the nuclear transactivation of ATGs such as LC3 and ATG12
LC could increase the amount of protein retention by inhibition of the proteolytic pathway
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