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In rheumatoid arthritis (RA), overproduction of the cytokine tumor necrosis factor (TNF) is a central event in pathogenesis, and endoplasmic reticulum (ER) rich T cells are the major releasers of TNF in inflamed joints
It has absolutely no direct interaction with the testicular Leydig cells, which are the body's testosterone factories
YAP can support compensatory hypertrophy by promoting aerobic glycolysis in pressure overload (15)
It has the highest mortality rate compared to other skin tumors, such as basal cell carcinoma and cutaneous squamous cell carcinoma (223, 224)
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